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"Junctophilin"
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca(2+) release.
BACKGROUND: Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 ryanodine receptors on the sarcoplasmic reticulum within junctional membrane complexes …
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