Khalid Azizi

Latest

• Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response.
• Simultaneous Isolation and Culture of Atrial Myocytes, Ventricular Myocytes, and Non-Myocytes from an Adult Mouse Heart.
• The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts.
• Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis.
• ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart.